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Comparison of a Point-of-care Cholesterol Meter With a Reference Laboratory Analyzer in Companion Psittaciformes

Abstract:
Abstract: Hypercholesterolemia is common in captive Psittaciformes. A point-of-care cholesterol analyzer would be useful to monitor hypercholesterolemia in psittacine birds. We compare a point-of-care cholesterol analyzer (PTS-Diagnostics CardioChek) with a reference laboratory analyzer (Roche Cobas c501) and provide initial assessment of precision and accuracy. A prospective method comparison study was designed to compare the CardioChek and Cobas c501 by assessment of clinical and analytical agreement using Passing-Bablock regression analysis and difference plots. Initial accuracy was assessed by running cholesterol standards, and initial precision was assessed by calculating between-run coefficient of variation on samples from selected birds. A total of 42 psittacine birds were sampled. No significant constant bias was found between the Cobas and CardioChek. However, a significant negative proportional bias was evident, suggesting that the point-of-care analyzer tended to underestimate cholesterol values. Lipemia and hemolysis had strong effects on increasing bias. Hematocrit, glucose level, and genus had no significant impact on bias, controlling for lipemia and hemolysis. Accuracy of the CardioCheck was suboptimal to that of the Cobas, but precision was good. When defining hypercholesterolemia as >8 mmol/L (309 mg/dL), the CardioChek had a sensitivity of 57% and specificity of 96%. There was neither analytical nor clinical agreement between the CardioChek and Cobas c501. Values obtained from the CardioChek cannot be used to determine or monitor hypercholesterolemia in parrots in the absence of analyzer-specific reference intervals.
Author Listing: Trinita Barboza;Hugues Beaufrère
Volume: 33
Pages: 14 - 7
DOI: 10.1647/2017-291
Language: English
Journal: Journal of Avian Medicine and Surgery

JOURNAL OF AVIAN MEDICINE AND SURGERY

J AVIAN MED SURG

影响因子:0.6
是否综述期刊:否
是否OA:否
是否预警:不在预警名单内
发行时间:1995
ISSN:1082-6742
发刊频率:Quarterly
收录数据库:SCIE/Scopus收录
出版国家/地区:UNITED STATES
出版社:Association of Avian Veterinarians

期刊介绍

The Journal of Avian Medicine and Surgery is an international journal of the medicine and surgery of both captive and wild birds. Published materials include scientific articles, case reports, editorials, abstracts, new research, and book reviews.

《鸟类医学与外科学杂志》是一本国际性的杂志,内容涉及圈养鸟类和野生鸟类的医学和外科学。发表的材料包括科学文章、病例报告、社论、摘要、新研究和书评。

年发文量 32
国人发稿量 -
国人发文占比 0%
自引率 16.7%
平均录取率 容易
平均审稿周期 >36周,或约稿
版面费 -
偏重研究方向 农林科学-兽医学
期刊官网 http://www.bioone.org/action/showPublisher?code=aavv
投稿链接 https://www.editorialmanager.com/AVIANMS

质量指标占比

研究类文章占比 OA被引用占比 撤稿占比 出版后修正文章占比
96.88% 0.00% 0.00% 0.00%

相关指数

影响因子
影响因子
年发文量
自引率
Cite Score

预警情况

时间 预警情况
2024年02月发布的2024版 不在预警名单中
2023年01月发布的2023版 不在预警名单中
2021年12月发布的2021版 不在预警名单中
2020年12月发布的2020版 不在预警名单中

JCR分区 WOS分区等级:Q3区

版本 按学科 分区
WOS期刊SCI分区
(2021-2022年最新版)
VETERINARY SCIENCES Q3

中科院分区

版本 大类学科 小类学科 Top期刊 综述期刊
农林科学
4区
VETERINARY SCIENCES
兽医学
4区
2021年12月
基础版
农林科学
4区
VETERINARY SCIENCES
兽医学
4区
2021年12月
升级版
农林科学
4区
VETERINARY SCIENCES
兽医学
4区
2020年12月
旧的升级版
农林科学
4区
VETERINARY SCIENCES
兽医学
4区
2022年12月
最新升级版
农林科学
4区
VETERINARY SCIENCES
兽医学
4区