Journal of Oral Biosciences 审稿速度-刊鹿论文编译

Role of nicotinic acetylcholine receptors for modulation of microcircuits in the agranular insular cortex.

Abstract:

BACKGROUND\nAcetylcholine (ACh) plays key roles in regulating neuronal excitability throughout the brain by acting muscarinic ACh receptors (mAChRs) and nicotinic ACh receptors (nAChRs). The insular cortex is an important brain region associated with sensory perception, self-awareness, cognitive function, motor control, and drug addiction. The insular cortex receives cholinergic inputs from the basal forebrain, the activation of which stimulates mAChRs and nAChRs in the insular cortex and modulates its microcircuits to perform various functions. Therefore, it is crucial to understand the cholinergic modulation of microcircuits in the insular cortex. To date, we have been focused on the role of nAChRs in modulating neural circuits in the mouse agranular insular cortex.\n\n\nHIGHLIGHT\nIn this review, we present data on cholinergic inputs to neocortical regions, including the insular cortex, and characteristics of mAChRs and nAChRs. In addition, we describe which type of neurons express functional nAChRs in layer III, V, and VI of the mouse agranular insular cortex and how activation of nAChRs regulates synaptic transmission and plasticity in the layer III, V, and VI pyramidal cells.\n\n\nCONCLUSION\nThe activation of nAChRs layer specifically modulates synaptic transmission and plasticity in the mouse agranular insular cortex. These synaptic mechanisms are critical to understand the modulating effects of ACh or nicotine on physiological and pathophysiological functions associated with the insular cortex.

Author Listing： Hiroki Toyoda

Volume： 61 1

Pages： \n 5-11\n

DOI： 10.1016/j.job.2018.12.001

Language： English

Journal： Journal of oral biosciences

Journal of Oral Biosciences

J ORAL BIOSCI

影响因子：2.3

是否综述期刊：否

是否OA：否

是否预警：不在预警名单内

发行时间：-

ISSN：1349-0079

发刊频率：-

收录数据库：ESCI/Scopus收录

出版国家/地区：-

出版社：Japanese Association for Oral Biology

期刊介绍

年发文量	93
国人发稿量	13
国人发文占比	14.29%
自引率	8.7%
平均录取率	-
平均审稿周期	-
版面费	US$2700
偏重研究方向	DENTISTRY, ORAL SURGERY & MEDICINE-
期刊官网	-
投稿链接	-

质量指标占比

研究类文章占比	OA被引用占比	撤稿占比	出版后修正文章占比
100.00%	15.58%	-	-

预警情况

时间	预警情况
2025年03月发布的2025版	不在预警名单中
2024年02月发布的2024版	不在预警名单中
2023年01月发布的2023版	不在预警名单中
2021年12月发布的2021版	不在预警名单中
2020年12月发布的2020版	不在预警名单中

JCR分区 WOS分区等级：Q2区

版本	按学科	分区
WOS期刊SCI分区（2021-2022年最新版）
	DENTISTRY, ORAL SURGERY & MEDICINE	Q2

中科院分区

版本	大类学科	小类学科	Top期刊	综述期刊
暂无数据