咨询客服 咨询客服

Complete Unsteady One-Dimensional Model of the Net Aortic Pressure Drop

Abstract:
Background: A large amount of engineering and medical research has been devoted to the assessment of aortic valve stenosis severity in the past decades. The net transvalvular pressure drop has been recognized as one of the parameters that better reflect stenosis effects on left ventricle overload, and its adoption in clinical assessment of stenosis has been proposed. Flow unsteadiness has been shown to have a non-negligible impact on the net drop; however, a simple formulation for net drop calculation that includes not only flow pulsatility but also the effects of valve dynamics is still lacking. Objective: The present contribution is hence aimed at developing a complete unsteady one-dimensional model of the net aortic transvalvular pressure drop that just requires non-invasive data to be implemented. Methods: Transvalvular flow is described as a jet of incompressible viscous fluid through a circular orifice placed in a concentric rigid circular tube. The classical one-dimensional mass and total head conservation equations are applied. The effective orifice area and transvalvular flow rate are assumed to vary with time throughout the ejection period. Results: The model is found to capture pressure drop oscillations occurring when the valve opens/closes and/or leaflets flutter, thanks to the inclusion of valve dynamics effects. The model is also proposed as a numerical tool for the calculation of the instantaneous effective orifice area once net pressure drop and flow rate are known. Conclusion: The model may contribute to the improvement of non-invasive aortic stenosis assessment.
Author Listing: Francesca Maria Susin
Volume: 13
Pages: 83-93
DOI: 10.2174/1874120701913010083
Language: English
Journal: The Open Biomedical Engineering Journal

Open Biomedical Engineering Journal

影响因子:0.0
是否综述期刊:否
是否OA:是
是否预警:不在预警名单内
发行时间:-
ISSN:1874-1207
发刊频率:-
收录数据库:Scopus收录
出版国家/地区:-
出版社:Bentham

期刊介绍

年发文量 -
国人发稿量 -
国人发文占比 -
自引率 0.0%
平均录取率 -
平均审稿周期 -
版面费 -
偏重研究方向 Medicine-Medicine (miscellaneous)
期刊官网 -
投稿链接 -

质量指标占比

研究类文章占比 OA被引用占比 撤稿占比 出版后修正文章占比
0.00% 0.00% - -

相关指数

影响因子
影响因子
年发文量
自引率
Cite Score

预警情况

时间 预警情况
2025年03月发布的2025版 不在预警名单中
2024年02月发布的2024版 不在预警名单中
2023年01月发布的2023版 不在预警名单中
2021年12月发布的2021版 不在预警名单中
2020年12月发布的2020版 不在预警名单中

JCR分区 WOS分区等级:Q0区

版本 按学科 分区
WOS期刊SCI分区
(2021-2022年最新版)

中科院分区

版本 大类学科 小类学科 Top期刊 综述期刊
暂无数据