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Acute Ischemic Stroke in Pregnancy

Abstract:
Stroke is an uncommon but serious potential complication of pregnancy. The management of acute ischemic stroke in pregnant women remains a complex challenge that extends beyond the limits of clinical trial evidence. Patient 1 was a 29-year-old woman 27 weeks into her first pregnancy, without remarkable past medical history or vascular risk factors. She was admitted 1 h after sudden onset of a left total anterior circulation syndrome (National Institute of Health Stroke Scale [NIHSS] score of 23). CT and angio-CT scans were normal. Thrombolysis was performed, with mild clinical improvement. Brain MRI showed multi-territorial embolic events. Extended blood panel, cervical-transcranial ultrasound, 48-h ECG monitoring, and transthoracic echocardiogram were unremarkable. She was started on aspirin and low-molecular-weight heparin (LMWH), giving birth to a healthy child 10 weeks later. Patient 2 was a 45-year-old woman 34 weeks into her pregnancy, without remarkable past medical history or vascular risk factors. She was admitted 30 min after sudden onset of a left partial anterior circulation syndrome, already partially recovered (NIHSS score of 4). The CT scan showed only a subacute right incidental middle cerebral artery infarct, while the angio-CT confirmed a left M3 branch occlusion. Thrombolysis and thrombectomy were contraindicated by the recent contralateral infarct, mild deficits, and distal occlusion site. Brain MRI also suggested an embolic etiology and LMWH was started. Extended blood panel, 48-h ECG monitoring, and transthoracic echocardiogram were normal. She gave birth to a healthy baby 4 weeks later. These cases emphasize the growing real-world evidence of the emergent use of CT, IV contrast, and recombinant tissue plasminogen activator in pregnant women with acute stroke, while also illustrating the importance of an individualized management, accounting for the safety of both mother and child.
Author Listing: Rita Rodrigues;Renata Souto Silva;Luís Fontão;Luis Ruano;José Mário Roriz
Volume: 11
Pages: 37 - 40
DOI: 10.1159/000496386
Language: English
Journal: Case Reports in Neurology

Case Reports in Neurology

影响因子:0.7
是否综述期刊:否
是否OA:是
是否预警:不在预警名单内
发行时间:-
ISSN:1662-680X
发刊频率:-
收录数据库:ESCI/Scopus收录/DOAJ开放期刊
出版国家/地区:Switzerland
出版社:Karger

期刊介绍

年发文量 33
国人发稿量 -
国人发文占比 0%
自引率 0.0%
平均录取率 -
平均审稿周期 14 Weeks
版面费 -
偏重研究方向 Medicine-Neurology (clinical)
期刊官网 http://www.karger.com/crn
投稿链接 -

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研究类文章占比 OA被引用占比 撤稿占比 出版后修正文章占比
100.00% 100.00% - -

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时间 预警情况
2025年03月发布的2025版 不在预警名单中
2024年02月发布的2024版 不在预警名单中
2023年01月发布的2023版 不在预警名单中
2021年12月发布的2021版 不在预警名单中
2020年12月发布的2020版 不在预警名单中

JCR分区 WOS分区等级:Q4区

版本 按学科 分区
WOS期刊SCI分区
(2021-2022年最新版)
CLINICAL NEUROLOGY Q4

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