Current Chemical Biology 怎么样-刊鹿论文编译

CRISPR-Cas Technology: A Role in Transcriptional Recording and Chromatin Remodeling Events

Abstract:

An elegant paper by Schmidt et al. [8] clearly elucidates the importance of transcriptional recording within Escherichia coli to decipher the complex cellular process. However, the authors address the CRISPR spacer acquisition-mediated recording of transcriptional events by using well designed experimental strategies. In the current perspectives, these tools and evidence of transcriptional recoding will boost to both basic and translational aspects of biology, where a plethora of stimuli change our cellular responses, including transcriptional events and thereafter molecular recording by using synthetic tools like CRISPR editing tools. Furthermore, the author would like to suggest that the existence and need of molecular recorder within a cell can be for both transcriptional and epigenetic events that would be besides earlier reported evidence on the molecular eraser, writer and reader in our genome. On the same line, there is a possibility of the existence of the molecular recorder in the nucleus that records many events including transcriptional events and the epigenetic process including chromatin remodeling [7-11].

Author Listing： Nilesh Kumar Sharma

Volume： 13

Pages： 185-186

DOI： 10.2174/2212796813666190823091033

Language： English

Journal： Current Chemical Biology

Current Chemical Biology

影响因子：0.0

是否综述期刊：否

是否OA：否

是否预警：不在预警名单内

发行时间：-

ISSN：2212-7968

发刊频率：-

收录数据库：Scopus收录

出版国家/地区：-

出版社：Bentham

期刊介绍

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自引率	0.0%
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偏重研究方向	Medicine-Biochemistry (medical)
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2025年03月发布的2025版	不在预警名单中
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2020年12月发布的2020版	不在预警名单中

JCR分区 WOS分区等级：Q0区

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WOS期刊SCI分区（2021-2022年最新版）

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