Egyptian Journal of Histology 投稿模板-刊鹿论文编译

The Effect of Diet Coke and Monosodium Glutamate on the Cerebellar Cortex of Adult Male Albino Rats. Histological and Immuno-histochemical Study

Abstract:

Background: The consumption of fast- food is increasing among children, adolescents and adults. Carbonated drinks as Diet Coke are widely consumed with fast food. One of the thousands of chemicals used in our new high-tech foods is the monosodium glutamate (MSG).\xa0\xa0Aim of the study: This study was conducted to investigate the effect of Diet Coke and monosodium glutamate salt either separately or in combination on the cerebellar cortex of adult male albino rats.Materials and Methods: Forty adult male albino rats were divided into four groups. Group I: control group. Group II (Diet Coke group) which was subdivided into: subgroup IIA: each rat received 2.5 ml of Diet Coke twice daily by oral gavage and subgroup IIB: rats received Diet Coke instead of water throughout the day. Group III (MSG group): rats received MSG salt solution (3 gm MSG / kgm) by oral gavage once daily. Group IV (combination group) rats received combination of MSG solution and Diet Coke. This group was subdivided into two subgroups. Subgroup IVA: rats received MSG salt solution in the same dose as group III and 2.5 ml of Diet Coke twice daily, by oral gavage. Subgroup IVB: rats received MSG salt solution in the same dose as group III and Diet Coke instead of water throughout the day. At the end of the experiment (21 days) cerebella were dissected out and processed for histological, immunohistochemical and morphometric studies.\xa0\xa0Results: Histological examination of the cerebellar cortex revealed that both Diet Coke and MSG either separately or in combination resulted in degenerative changes that were more significant in the combination group.Conclusion: Diet Coke and MSG induced degenerative changes in the cerebellar cortex that was more significant in their combination.

Author Listing： Noha Ali Abd El-Wahed;Esmat Zaki Geith;Nagwa Kostandy Kalleny;Hadwa Ali Abd Al-Khalek

Volume： 42

Pages： 437-452

DOI： 10.21608/ejh.2019.7279.1071

Language： English

Journal： the egyptian journal of histology

Egyptian Journal of Histology

影响因子：0.0

是否综述期刊：否

是否OA：否

是否预警：不在预警名单内

发行时间：-

ISSN：1110-0559

发刊频率：-

收录数据库：Scopus收录

出版国家/地区：-

出版社：Wolters Kluwer Health

期刊介绍

年发文量	-
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自引率	0.0%
平均录取率	-
平均审稿周期	-
版面费	-
偏重研究方向	Medicine-Histology
期刊官网	-
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研究类文章占比	OA被引用占比	撤稿占比	出版后修正文章占比
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预警情况

时间	预警情况
2024年02月发布的2024版	不在预警名单中
2023年01月发布的2023版	不在预警名单中
2021年12月发布的2021版	不在预警名单中
2020年12月发布的2020版	不在预警名单中

JCR分区 WOS分区等级：Q0区

版本	按学科	分区
WOS期刊SCI分区（2021-2022年最新版）

中科院分区

版本	大类学科	小类学科	Top期刊	综述期刊
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