International Journal of Nephrology and Renovascular Disease 版面费-刊鹿论文编译

Hypertensive retinopathy and associated factors among nondiabetic chronic kidney disease patients seen at a tertiary hospital in Tanzania: a cross-sectional study

Abstract:

Background: Hypertensive retinopathy is a known marker of cardiovascular disease, and among unselected patients with chronic kidney disease (CKD) more severe retinopathy has been associated with lower estimated glomerular filtration rate (eGFR). This association has, however, not been widely studied among nondiabetic hypertensive patients with CKD, especially in sub-Saharan Africa. We aimed to determine the prevalence and severity of hypertensive retinopathy and its relationship with eGFR among nondiabetic CKD patients seen at Muhimbili National Hospital in Dar es Salaam, Tanzania. Methods: A hospital-based cross-sectional study was conducted among nondiabetic CKD adult (≥18 years) patients with hypertension. A structured questionnaire was used to record patients’ demographic characteristics and their cardiovascular risk profile. eGFR was calculated using the Modification of Diet in the Renal Disease (MDRD) equation and only patients with CKD stage 3 or more were enrolled in the study. Grading of retinopathy was done using the Keith–Wagener classification. Results: In total, 224 patients fulfilled the inclusion criteria and were enrolled. Their mean age was 45.8±14.1 years, and 59.4% were men. The proportions of patients with stage 3, 4, and 5 CKD were 21.4%, 19.6%, and 58.9%, respectively. Hypertensive retinopathy was present in 157 (70.1%) patients and the proportions with grade I, grade II, grade III, and grade IV retinopathy were 17.9%, 18.8%, 19.6%, and 13.8%, respectively. The severity of retinopathy increased with decreasing levels of eGFR, and in multivariate logistic regression analysis, factors found to be independently associated with ≥grade II hypertensive retinopathy were more severe CKD, higher hypertension grades, and alcohol use, all p<0.05. Conclusion: The prevalence of hypertensive retinopathy is high among nondiabetic CKD patients seen at a tertiary hospital in Tanzania and is independently associated with CKD severity. Retinopathy grade can be used as a marker of CKD severity among these patients.

Author Listing： Pilly Chillo;Ame Ismail;Anna Sanyiwa;Paschal Ruggajo;Appolinary Kamuhabwa

Volume： 12

Pages： 79 - 86

DOI： 10.2147/IJNRD.S196841

Language： English

Journal： International Journal of Nephrology and Renovascular Disease

International Journal of Nephrology and Renovascular Disease

INT J NEPHROL RENOV

影响因子：2.5

是否综述期刊：否

是否OA：是

是否预警：不在预警名单内

发行时间：-

ISSN：1178-7058

发刊频率：-

收录数据库：ESCI/Scopus收录/DOAJ开放期刊

出版国家/地区：United Kingdom

出版社：Dove Medical Press

期刊介绍

年发文量	31
国人发稿量	2
国人发文占比	8%
自引率	0.0%
平均录取率	-
平均审稿周期	16 Weeks
版面费	US$2320
偏重研究方向	UROLOGY & NEPHROLOGY-
期刊官网	http://www.dovepress.com/international-journal-of-nephrology-and-renovascular-disease-journal
投稿链接	-

质量指标占比

研究类文章占比	OA被引用占比	撤稿占比	出版后修正文章占比
83.87%	100.00%	-	-

预警情况

时间	预警情况
2025年03月发布的2025版	不在预警名单中
2024年02月发布的2024版	不在预警名单中
2023年01月发布的2023版	不在预警名单中
2021年12月发布的2021版	不在预警名单中
2020年12月发布的2020版	不在预警名单中

JCR分区 WOS分区等级：Q2区

版本	按学科	分区
WOS期刊SCI分区（2021-2022年最新版）
	UROLOGY & NEPHROLOGY	Q3

中科院分区

版本	大类学科	小类学科	Top期刊	综述期刊
暂无数据